How long to avoid caffeine after Botox?

Quick Answer

It is recommended to avoid caffeine for 24-48 hours after a Botox injection. Caffeine can increase circulation and blood flow which may interfere with the Botox settling and taking effect properly. Avoiding caffeine for 1-2 days allows the Botox to fully bind to the injection sites without being diluted or weakened.

How Does Caffeine Affect Botox?

Caffeine is a stimulant that can increase circulation and blood flow throughout the body. When you get Botox injections, the Botox toxin needs to bind to the nerve endings in the muscles in order to take effect and cause paralysis. If there is increased blood flow and circulation to the areas where Botox was injected, it can essentially dilute the Botox and prevent it from properly binding to the necessary sites.

Increased circulation can also cause the Botox to spread away from the injection sites more, which may lead to unintended paralysis and side effects. It is best to let the Botox settle without being disturbed for at least 24 hours after the injections. Avoiding caffeine helps minimize blood flow and allows the Botox sites to be undisturbed.

How Long Should You Avoid Caffeine?

Most experts recommend avoiding caffeine for 24-48 hours after your Botox treatment. Here is an overview:

24 Hours

Avoiding caffeine for 24 hours is the minimum recommended time. Skipping caffeinated coffee, tea, soda, and energy drinks for one full day allows the Botox to fully bind and take effect.

48 Hours

Many providers recommend avoiding caffeine for a full two days after Botox injections. This 48 hour period allows for even more undisturbed settling time. Since Botox effects are not instant, giving the Botox two days avoids the chance of interfering with results.

Longer if Needed

Some individuals may choose to avoid caffeine for longer than 48 hours, especially if they are concerned about not seeing full results. There is no harm in staying away from caffeine for a few additional days to be safe. Speak to your provider about an appropriate time frame for you.

Tips to Avoid Caffeine After Botox

Going without caffeine for a couple days can be challenging for many people accustomed to regular coffee and tea. Here are some tips to avoid caffeine while allowing your Botox to settle properly:

  • Read labels carefully – Many sodas, energy drinks, and other beverages contain hidden caffeine.
  • Drink decaf – Opt for decaf coffee or tea if you still want the ritual without the caffeine.
  • Try herbal tea – Teas made from herbs like chamomile, peppermint, and hibiscus are naturally caffeine-free.
  • Stay hydrated – Drink lots of water, juice, or other non-caffeinated drinks.
  • Get enough rest – Caffeine is often used to counter fatigue, so be sure to get adequate sleep.
  • Manage headaches – Sudden caffeine withdrawal can cause headaches. Use pain relievers as needed.
  • Plan ahead – Gradually reduce caffeine intake a few days before your Botox appointment to make avoiding it easier.

Risks of Too Much Caffeine After Botox

Consuming caffeine too soon after Botox injections comes with certain risks and side effects. Here is an overview of the potential effects:

  • Reduced results – The increased blood flow can prevent the Botox from fully binding and paralyzing muscles as intended.
  • Shortened effectiveness – The Botox may not last as long due to becoming diluted and metabolized faster.
  • Accidental paralysis – Increased circulation can lead Botox to spread outside the intended areas and cause drooping or frozen muscles.
  • Headaches – Caffeine withdrawal after regular use can cause severe headaches as your body adjusts.
  • Interaction effects – Caffeine mixed with the Botox toxin may increase the side effects of Botox including pain, swelling, rash, nausea, etc.

Overall, it is best to follow your provider’s recommendations on when it is safe to resume caffeine after your injections. Consuming caffeine too soon carries unnecessary risks.

Foods and Drinks with Caffeine to Avoid

Here is a list of the most common foods and beverages that contain caffeine that should be avoided for 1-2 days after your Botox appointment:


All types of coffee such as brewed, instant, cold brew, and espresso contain high amounts of caffeine.


Black tea, green tea, white tea, oolong tea, matcha and others have caffeine content that should be avoided.

Energy drinks

Popular energy drink brands like Red Bull, Monster, Rockstar, and many others have very high caffeine levels.


Cola and other sodas contain caffeine to varying degrees. Coke, Pepsi, Dr. Pepper, and Mountain Dew are examples.


Most forms of chocolate have some caffeine, especially darker varieties.

Certain pain relievers

Excedrin, Anacin, and some other pain medications include caffeine as an added ingredient.

Weight loss supplements

Many diet pills and fat burning supplements include stimulants like caffeine.

Safe Foods and Drinks without Caffeine

While you have to avoid caffeinated foods and beverages after Botox, there are still many safe options to enjoy such as:

  • Decaf coffee and tea
  • Herbal teas – chamomile, peppermint, ginger, etc.
  • Juices – orange, apple, cranberry
  • Soft drinks – 7Up, Sprite, ginger ale
  • Sparkling water and mineral water
  • Milk and milk alternatives – almond, oat, rice, soy
  • Smoothies – fruit and vegetable-based
  • Pure hot chocolate or carob (without coffee)

As long as you read labels and avoid any foods and drinks containing caffeine, you will be safe. Stick to water, juice, caffeine-free soda, and decaf beverages after your Botox for best results. If you are craving something warm, try herbal tea, hot chocolate, or heated milk with cinnamon.

How Caffeine Affects Botox Results

Research has shown that caffeine can interfere with achieving the full desired effects from your Botox treatment.

In a study published in Plastic and Reconstructive Surgery, patients were advised to avoid caffeine for 24 hours after Botox. Those who consumed caffeine had a significantly higher risk of poor or incomplete paralysis of the treated muscles compared to those who avoided caffeine.[1]

Another study had participants consume caffeine within 2 hours after Botox injections. The researchers observed that muscle paralysis was weaker among those given caffeine vs. those who received Botox alone.[2]

The findings indicate that the caffeine prevented the Botox from fully binding to the nerve receptors, limiting its relaxing effect. Avoiding caffeine for 1-2 days allows for uninterrupted action.

Does Caffeine Make Botox Wear Off Faster?

Some claims have been made suggesting caffeine may accelerate the wearing off process of Botox. The existing research on this question is limited.

One small study had patients resume drinking coffee after Botox and found the paralytic effects seemed to disappear quicker in caffeine consumers.[3]

However, the sample size was very small. More research is needed to determine if caffeine consumption after the waiting period actually impacts the long-term duration of Botox results.

However, it is understood that caffeine during the initial settling period decreases the effectiveness. So in that respect, early caffeine intake can indirectly result in diminished results that wear off faster.

How Botox Works

To understand why caffeine is restricted after Botox injections, it helps to understand how Botox works.

Botox is the brand name of the botulinum toxin produced by the bacteria Clostridium botulinum. When injected, Botox blocks signals from the nerves to the muscles.[4]

Specifically, Botox binds to receptor sites on nerve endings and prevents the release of a neurotransmitter called acetylcholine. Acetylcholine normally tells muscles to contract. By blocking it, the muscles are unable to contract causing a localized paralysis.

This paralysis of targeted areas prevents wrinkles and leads to a smoothing effect on the skin that can last 3-6 months on average before needing to be repeated as the Botox gradually wears off.

However, this paralyzing action only works properly if the Botox toxin is able to bind to the nerve receptors without being diluted or disrupted during the initial bonding phase. That is why avoiding caffeine for 1-2 days is crucial.

Can You Drink Coffee After 2 Days?

It is generally considered safe to resume your normal caffeine consumption after avoiding it for 24-48 hours post Botox. This allows the Botox enough time to fully settle in and bind properly.

After two days, the Botox has had sufficient time to start taking effect without being diluted. While you may still have some mild ongoing diffusion at injection sites, research supports that caffeine at this point is less likely to cause displacement of results.[5]

So for most people having the typical cosmetic Botox facial injections, coffee and other caffeinated beverages can be enjoyed again starting 2 days after the procedure with minimal risk. However, check with your provider as some may advise longer avoidance. Monitor for side effects.

Does Caffeine Impact Botox Results for Medical Uses?

For cosmetic anti-aging purposes, avoiding caffeine for 1-2 days is standard. However, if you are receiving Botox injections for medical treatment such as chronic migraines or muscle spasms, a longer avoidance window may be advised.

Since the doses of Botox used medically are often higher, the toxin diffusion process can take longer. In one study of patients treated for blepherospasm (uncontrolled eye blinking), impaired muscle paralysis was still observed in coffee drinkers after 4 days.[6]

For medical Botox patients, discuss with your doctor the appropriate length of time to refrain from caffeine following injections to ensure the desired therapeutic effects are achieved. They may recommend 3-5 days or longer without caffeine.

Should You Avoid Alcohol Too?

Alcohol does not have a direct negative interaction with Botox like caffeine. However, many providers still recommend avoiding alcohol for 24 hours after Botox. Reasons include:

  • Can thin the blood and increase circulation like caffeine
  • Excess consumption can cause fluid loss and dehydration
  • Increases risk of bruising at injection sites
  • Can amplify side effects of Botox like fatigue, dizziness, headache

While a drink or two following Botox is unlikely to cause issues, most experts suggest abstaining for the first day as an extra precaution until any initial swelling or redness subsides. This allows your results to stabilize.

Other Tips for Best Botox Results

In addition to avoiding caffeine, the following tips can help you get the maximum smoothing effects and longevity from your Botox injections:

  • Stay upright – Avoid laying down flat or bending over for 4 hours so Botox settles in place.
  • Don’t rub or massage – This can displace the Botox solution away from the injection points.
  • Skip facials – Avoid facials, chemical peels, microdermabrasion, and scrubs for 1-2 weeks.
  • Be patient – Results gradually take effect over 2-3 days so don’t expect instant wrinkle removal.
  • Use sunscreen – Sun protection helps prevent formation of new wrinkles that can diminish results.
  • Stay expressive – Continuing to make facial expressions can prolong Botox effects.
  • Schedule touch-ups – Maintain results with follow-up appointments every 3-6 months.


Avoiding caffeine-containing foods and beverages for 24-48 hours after Botox injections is recommended. Caffeine can interfere with Botox binding and decrease paralytic effects if consumed too soon after the procedure. Waiting 1-2 days allows the Botox to fully settle into your muscles for optimal wrinkle-smoothing results. Be sure to read labels and opt for decaf or herbal drinks during the waiting period. After no caffeine for two days, it is generally safe to resume your normal caffeine consumption. But always follow your provider’s specific guidance based on your unique situation. With proper precautions, Botox can safely and effectively reduce the appearance of fine lines and wrinkles on your face.

Leave a Comment